Management of chronic hepatitis C

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Management of chronic hepatitis C.

Hepatitis C virus (HCV) infection is transmitted primarily through percutaneous exposure to blood, and most infections are associated with injection drug use. Progression to chronic HCV occurs in 55% to 86% of infected people, and persistent infection is a major cause of cirrhosis, end stage liver disease, and hepatocellular carcinoma. The detection of HCV antibodies should be performed initial...

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Management of chronic hepatitis C: consensus guidelines.

Since the last consensus conference on the management of chronic viral hepatitis, a number of studies looking at modifications of the standard course of treatment have been published. These changes have been sufficiently substantive to warrant review to determine whether any changes in the recommended treatment algorithms are needed. A consensus development conference was held in January 2007, ...

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Chronic viral hepatitis C: management update.

The management of chronic viral hepatitis C is evolving rapidly. Monotherapy with interferon, the accepted standard of treatment until recently, achieves only a modest sustained virological response rate of 15%. Combination treatment with alpha-2b interferon and ribavirin has been shown to increase sustained response rates to 40% in patients who have never been treated with interferon and to 50...

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Management of chronic hepatitis C in HIV-infected patients.

Coinfection with hepatitis C virus (HCV) is common among persons infected with the human immunodeficiency virus (HIV). Treatment regimens based on standard interferon α (IFN α) and ribavirin (RBV) are recommended for chronic HCV, but they pose special concerns in patients coinfected with HIV, particularly those patients who are receiving antiretroviral therapy. Recently, several randomized stud...

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[An update on the management of chronic hepatitis C].

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 2005

ISSN: 0032-5473

DOI: 10.1136/pgmj.2004.025403